If the practice per se is not viable, then SRs will be of little value. Genomically humanized mice: technologies and promises.
We will now present the empirical evidence and later seek to place it within the context of complexity science and evolutionary biology.
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We acknowledge that animals can successfully be used in categories 3-9 in table 2 and that SRs could positively impact on such use and that some calling for SRs and standardization advocate for such on this basis.
However, it appears that the main emphasis among those calling for SRs and standardization is to improve predictive value.